Natural Language Processing (NLP) has experienced explosive growth in recent years. While the field has been around for decades, recent advances in NLP techniques as well as advanced computational resources have re-engaged academics, industry, and the general public. The field of Geographic Information Science has played a small but important role in the growth of this domain. Combining NLP techniques with existing geographic methodologies and knowledge has contributed substantially to many geospatial applications currently in use today. In this entry, we provide an overview of current application areas for natural language processing in GIScience. We provide some examples and discuss some of the challenges in this area.