Local multivariate statistical models are increasingly encountered in geographical research to estimate spatially varying relationships between a response variable and its associated predictor variables. In geography and many other disciplines, such models have been largely embedded within the framework of regression and can reveal significantly more information about the determinants of observed spatial distribution of the dependent variable than their global regression model counterparts. This section introduces one type of local statistical modeling framework: Geographically Weighted Regression (GWR). Models within this framework estimate location-specific parameter estimates for each covariate, local diagnostic statistics, and bandwidth parameters as indicators of the spatial scales at which the modeled processes operate. These models provide an effective means to estimate how the same factors may evoke different responses across locations and by so doing, bring to the fore the role of geographical context on human preferences and behavior.